Life Cycle Assessment of a Coke Cleaning Agent

The life cycle assessment of the coke cleaning agent developed by a university-enterprise cooperation project was conducted. This cleaning agent has the characteristics of phosphorus-free, environmentally friendly, and broad market prospects. The life cycle assessment of the established model showed that the GWP of producing 1kg of coke cleaning agent is 1.19 kg CO2 eq, PED is 13.17 MJ, WU is 186.74 kg, AP is 3.63E-03 kg SO2 eq, ADP is 7.75E-05 kg antimony eq, EP is 1.30E-03 kg PO43-eq, RI is 1.16E-03 kg PM2.5 eq, ODP is 4.63E-06 kg CFC-11 eq, and POFP is 1.85E-03 kg NMVOC eq .The uncertainty of the results is between 4.20% and 24.05%. The carbon footprint (GWP) analysis showed that the production process of isotridecanol polyoxyethylene ether, isopropanol, fatty alcohol polyoxyethylene ether M and isodecanol polyoxyethylene ether contributed significantly. The average sensitivity analysis showed that the most influential processes were sodium lauryl amphoacetate, isopropanol, and tripropylene glycol methyl ether. Citation: Gong, Y., Yang, C., Qu, Y., Li, J., Yang, B., Ding, Y., and Zhang, B. (2022). Life Cycle Assessment of a Coke Cleaning Agent. Trends in Renewable Energy, 8(1), 67-83. DOI: 10.17737/tre.2022.8.1.0014

Life Cycle Assessment of A Hydrocarbon-based Electrified Cleaning Agent

The electrified cleaning agent requires a moderate volatilization rate, low ozone-depleting substances value, non-flammable, non-explosive and other characteristics. This study performed a whole life cycle assessment on a hydrocarbon-based electrified cleaning agent. The life cycle model is cradle-to-grave, and the background data sets include power grid, transportation, high-density polyethylene, chemicals, etc. The analysis shows that the global warming potential (GWP) of the life cycle of 1 kg of electrified cleaning agent is 2.08 kg CO2 eq, acidification potential (AP) is 9.49E-03 kg SO2 eq, eutrophication potential (EP) is 1.18E-03 kg PO43-eq, respirable inorganic matter (RI) is 2.13E- 03 kg PM2.5 eq, ozone depletion potential (ODP) is 4.91E-05 kg CFC-11 eq, photochemical ozone formation potential (POFP) is 2.89E-02 kg NMVOC eq, ionizing radiation-human health potential (IRP) is 3.16E-02 kg U235 eq, ecotoxicity (ET) is 2.69E-01 CTUe, human toxicity-carcinogenic (HT-cancer) is 4.32E-08 CTUh, and human toxicity-non-carcinogenic (HT-non cancer) is 2.31E-07 CTUh. The uncertainty of the results is between 3.46-9.95%.The four processes of tetrachloroethylene production, D40 solvent oil production, tetrachloroethylene environmental discharge during product use, and electricity usage during product disposal have substantial effects on each LCA indicator, so they are the focus of process improvement. Changes in power consumption during production and transportation distance of raw materials have little effect on total carbon emissions. Compared with the production process of single-solvent electrified cleaning agent tetrachloroethylene and n-bromopropane, the production of the electrified cleaning agent developed in this study has its own advantages in terms of carbon footprint and other environmental impact indicators. Carbon emissions mainly come from the power consumption of each process, natural gas production and combustion, and other energy materials for heating. It is recommended to use renewable raw materials instead of crude oil to obtain carbon credits based on geographical advantages, and try to use production processes with lower carbon emissions, while the exhaust gas from the traditional production process is strictly absorbed and purified before being discharged

Process Design of Microalgae Slurry Pump

Microalgae are a renewable source of dietary supplements, bioactive compounds, and potential energy. Once harvested, the microalgal medium is dewatered to form a slurry for downstream processing. This article outlines a process design for pumping the microalgae slurry. The pump requirements for delivering the Chlorella slurry with 5, 10 or 20 wt% solids at one tonne per hour (1,000 kg/h) and 10 bar were calculated. The 5 wt% microalgae slurry is a Newtonian fluid with a viscosity of 1.95 mPa×s. The 10 wt% and 20 wt% microalgae slurries are non-Newtonian fluids, whose viscosity depends on the shear rate (g). The viscosity of 10 wt% and 20 wt% microalgae slurries is 1.504 (g = 50 s-1)/1.155 (g = 100 s-1) and 1.844 (g = 50 s-1)/1.219 (g = 100 s-1) mPa×s, respectively. The pump power requirements are mainly governed by the delivery pressure. The effect of the pipe length and the number of elbows is negligible. The effective power of the pump is calculated as 0.267-0.275 kW. To fulfill this duty, a ZGB type single-stage single-suction centrifugal slurry pump can be selected, which would provide enough shear rate to reduce the viscosity of the microalgae slurry and give required shaft power. Citation: Li, J., Qu, Y., Gong, Y., Yang, C., Yang, B., Liu, P., Zhang, B., and Ding, Y. (2020). Process Design of Microalgae Slurry Pump. Trends in Renewable Energy, 6(3), 234-244. DOI: 10.17737/tre.2020.6.3.0012

Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways

FGF21 is recently discovered with pleiotropic effects on glucose and lipid metabolism. However, the potential protective effect of FGF21 against D-gal-induced injury in the liver has not been demonstrated. The aim of this study is to investigate the pathophysiological role of FGF21 on hepatic oxidative injury and apoptosis in mice induced by D-gal. The 3-month-old Kunming mice were subcutaneously injected with D-gal (180 mg kg(-1) d(1)) for 8 weeks and administered simultaneously with FGF21 (5 or 1 mg kg(-1) d(1)). Our results showed that the administration of FGF21 significantly alleviated histological lesion including structure damage, degeneration, and necrosis of hepatocytes induced by D-gal, and attenuated the elevation of liver injury markers, serum AST, and ALP in a dosedependent manner. FGF21 treatment also suppressed D-galinduced profound elevation of ROS production and oxidative stress, as evidenced by an increase of the MDA level and depletion of the intracellular GSH level in the liver, and restored the activities of antioxidant enzymes SOD, CAT, GSH-Px, and T-AOC. Moreover, FGF21 treatment increased the nuclear abundance of Nrf2 and subsequent up regulation of several antioxidant genes. Furthermore, a TUNEL assay showed that D-gal-induced apoptosis in the mouse liver was significantly inhibited by FGF21. The expression of caspase-3 was markedly inhibited by the treatment of FGF21 in the liver of D-gal-treated mice. The levels of PI3K and PBK/Akt were also largely enhanced, which in turn inactivated pro-apoptotic signaling events, restoring the balance between pro-and anti-apoptotic Bcl-2 and Bax proteins in the liver of D-gal-treated mice. In conclusion, these results suggest that FGF21 protects the mouse liver against D-gal-induced hepatocyte oxidative stress via enhancing Nrf2-mediated antioxidant capacity and apoptosis via activating PI3K/Akt pathway

Mechanism of Regulation of Big-Conductance Ca2+-Activated K+ Channels by mTOR Complex 2 in Podocytes

Podocytes, dynamic polarized cells wrapped around glomerular capillaries, are an essential component of the glomerular filtration barrier. BK channels consist of one of the slit diaphragm (SD) proteins in podocytes, interact with the actin cytoskeleton, and play vital roles in glomerular filtration. Mechanistic target of rapamycin (mTOR) complexes regulate expression of SD proteins, as well as cytoskeleton structure, in podocytes. However, whether mTOR complexes regulate podocyte BK channels is still unclear. Here, we investigated the mechanism of mTOR complex regulation of BK channels via real-time PCR, western blot, immunofluorescence, and patch clamping. Inhibiting mTORC1 with rapamycin or downregulating Raptor had no significant effect on BK channel mRNA and protein levels and bioactivity. However, the dual inhibitor of mTORC1 and mTORC2 AZD8055 and short hairpin RNA targeting Rictor downregulated BK channel mRNA and protein levels and bioactivity. In addition, MK2206, GF109203X, and GSK650394, which are inhibitors of Akt, PKCα, and SGK1, respectively, were employed to test the downstream signaling pathway of mTORC2. MK2206 and GF109203X had no effect on BK channel protein levels. MK2206 caused an obvious decrease in the current density of the BK channels. Moreover, GSK650394 downregulated the BK channel protein and mRNA levels. These results indicate mTORC2 not only regulates the distribution of BK channels through Akt, but also modulates BK channel protein expression via SGK1 in podocytes

The Effect of Intensity, Frequency, Duration and Volume of Physical Activity in Children and Adolescents on Skeletal Muscle Fitness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Physical activity could improve the muscle fitness of youth, but the systematic analysis of physical activity elements and muscle fitness was limited. This systematic review and meta-analysis aim to explore the influence of physical activity elements on muscle fitness in children and adolescents. We analyzed literature in Embase, EBSCO, Web of Science, and PubMed databases from January 2000 to September 2020. Only randomized controlled studies with an active control group, which examined at least 1 muscle fitness evaluation index in individuals aged 5–18 years were included. Articles were evaluated using the Jaded scale. Weighted-mean standardized mean differences (SMDs) were calculated using random-effects models. Twenty-one studies and 2267 subjects were included. Physical activity had moderate effects on improving muscle fitness (SMD: 0.58–0.96, p < 0.05). Physical activity element subgroup analysis showed that high-intensity (SMD 0.68–0.99, p < 0.05) physical activity <3 times/week (SMD 0.68–0.99, p < 0.05), and <60 min/session (SMD 0.66–0.76, p < 0.01) effectively improved muscle fitness. Resistance training of ≥3 sets/session (SMD 0.93–2.90, p < 0.01) and <10 repetitions/set (SMD 0.93–1.29, p < 0.05) significantly improved muscle fitness. Low-frequency, high-intensity, and short-duration physical activity more effectively improves muscle fitness in children and adolescents. The major limitation of this meta-analysis was the low quality of included studies. The study was registered in PROSPERO with the registration number CRD42020206963 and was funded mainly by the Ministry of Education of Humanities and Social Science project, China

Progress of Stewart Vibration Platform in Aerospace Micro–Vibration Control

In order to support the development of high–precision spacecraft, the current state of the Stewart vibration isolation platform in the field of aerospace micro–vibration was surveyed. First, based on analyses of the causes and characteristics of spacecraft micro–vibration, the principles, characteristics, advantages and disadvantages of four vibration isolation technologies are summarized. Second, the development process of the Stewart vibration isolation platform, from structural proposal and theoretical calculation to application in various fields, is introduced. Then, the current state of kinematics, dynamics and braking control algorithms of the Stewart platform is investigated, and related work on rigid/flexible platforms in the field of aerospace micro–vibration is introduced in detail. Finally, the idea that the Stewart platform can be fabricated by 4D printing technology is proposed. The novel Stewart platform can be combined with artificial intelligence algorithms and advanced control strategies, allowing for further development in the direction of an integrated omnidirectional, full–frequency and multi–function platform with variable stiffness

Progress of Stewart Vibration Platform in Aerospace Micro–Vibration Control

In order to support the development of high–precision spacecraft, the current state of the Stewart vibration isolation platform in the field of aerospace micro–vibration was surveyed. First, based on analyses of the causes and characteristics of spacecraft micro–vibration, the principles, characteristics, advantages and disadvantages of four vibration isolation technologies are summarized. Second, the development process of the Stewart vibration isolation platform, from structural proposal and theoretical calculation to application in various fields, is introduced. Then, the current state of kinematics, dynamics and braking control algorithms of the Stewart platform is investigated, and related work on rigid/flexible platforms in the field of aerospace micro–vibration is introduced in detail. Finally, the idea that the Stewart platform can be fabricated by 4D printing technology is proposed. The novel Stewart platform can be combined with artificial intelligence algorithms and advanced control strategies, allowing for further development in the direction of an integrated omnidirectional, full–frequency and multi–function platform with variable stiffness

Homogenate-assisted Vacuum-powered Bubble Extraction of Moso Bamboo Flavonoids for On-line Scavenging Free Radical Capacity Analysis

A homogenate-assisted vacuum-powered bubble extraction (HVBE) method using ethanol was applied for extraction of flavonoids from Phyllostachys pubescens (P. pubescens) leaves. The mechanisms of homogenate-assisted extraction and vacuum-powered bubble generation were discussed in detail. Furthermore, a method for the rapid determination of flavonoids by HPLC was established. HVBE followed by HPLC was successfully applied for the extraction and quantification of four flavonoids in P. pubescens, including orientin, isoorientin, vitexin, and isovitexin. This method provides a fast and effective means for the preparation and determination of plant active components. Moreover, the on-line antioxidant capacity, including scavenging positive ion and negative ion free radical capacity of different fractions from the bamboo flavonoid extract was evaluated. Results showed that the scavenging DPPH˙ free radical capacity of vitexin and isovitexin was larger than that of isoorientin and orientin. On the contrary, the scavenging ABTS+˙free radical capacity of isoorientin and orientin was larger than that of vitexin and isovitexin